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Computational modeling to predict the functions and impact of drug transporters

Transport proteins are important mediators of cellular drug influx and efflux and play crucial roles in drug distribution, disposition and clearance. Drug-drug interactions have increasingly been found to occur at the transporter level and, hence, computational tools for studying drug-transporter in...

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Detalles Bibliográficos
Autores principales: Matsson, Pär, Bergström, Christel A S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559557/
https://www.ncbi.nlm.nih.gov/pubmed/26820893
http://dx.doi.org/10.1186/s40203-015-0012-3