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Amlexanox Suppresses Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss

The activity of protein kinases IKK-ε and TANK-binding kinase 1 (TBK1) has been shown to be associated with inflammatory diseases. As an inhibitor of IKK-ε and TBK1, amlexanox is an anti-inflammatory, anti-allergic, immunomodulator and used for treatment of ulcer, allergic rhinitis and asthma in cli...

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Detalles Bibliográficos
Autores principales: Zhang, Yong, Guan, Hanfeng, Li, Jing, Fang, Zhong, Chen, Wenjian, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559750/
https://www.ncbi.nlm.nih.gov/pubmed/26338477
http://dx.doi.org/10.1038/srep13575