A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis

Organ size determination is one of the most intriguing unsolved mysteries in biology. Aberrant activation of the major effector and transcription co-activator YAP in the Hippo pathway causes drastic organ enlargement in development and underlies tumorigenesis in many human cancers. However, how robu...

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Detalles Bibliográficos
Autores principales: Shen, Shuying, Guo, Xiaocan, Yan, Huan, Lu, Yi, Ji, Xinyan, Li, Li, Liang, Tingbo, Zhou, Dawang, Feng, Xin-Hua, Zhao, Jonathan C, Yu, Jindan, Gong, Xing-Guo, Zhang, Lei, Zhao, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559818/
https://www.ncbi.nlm.nih.gov/pubmed/26272168
http://dx.doi.org/10.1038/cr.2015.98

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559818/
https://www.ncbi.nlm.nih.gov/pubmed/26272168
http://dx.doi.org/10.1038/cr.2015.98

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