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Hitting the brakes: targeting microtubule motors in cancer

Despite the growing number of therapies that target cancer-specific pathways, cytotoxic treatments remain important clinical tools. The rationale for targeting cell proliferation by chemotherapeutic agents stems from the assumption that tumours harbour a greater fraction of actively dividing cells t...

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Detalles Bibliográficos
Autores principales: Chandrasekaran, Gayathri, Tátrai, Péter, Gergely, Fanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559828/
https://www.ncbi.nlm.nih.gov/pubmed/26180922
http://dx.doi.org/10.1038/bjc.2015.264