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Ruptured hepatic metastases of cutaneous melanoma during treatment with vemurafenib: an autopsy case report

BACKGROUND: The spontaneous rupture of hepatic metastases is rare compared to that of primary hepatic tumors. In addition, vemurafenib, a selective inhibitor of the mutant BRAF protein or gene product, has been reported to be extremely effective in patients with metastatic melanoma who harbor a BRAF...

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Detalles Bibliográficos
Autores principales: Nosaka, Takuto, Hiramatsu, Katsushi, Nemoto, Tomoyuki, Saito, Yasushi, Ozaki, Yoshihiko, Takahashi, Kazuto, Naito, Tatsushi, Ofuji, Kazuya, Matsuda, Hidetaka, Ohtani, Masahiro, Suto, Hiroyuki, Imamura, Yoshiaki, Nakamoto, Yasunari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559873/
https://www.ncbi.nlm.nih.gov/pubmed/26346246
http://dx.doi.org/10.1186/s12907-015-0015-3