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CoSREM: a graph mining algorithm for the discovery of combinatorial splicing regulatory elements
BACKGROUND: Alternative splicing (AS) is a post-transcriptional regulatory mechanism for gene expression regulation. Splicing decisions are affected by the combinatorial behavior of different splicing factors that bind to multiple binding sites in exons and introns. These binding sites are called sp...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559876/ https://www.ncbi.nlm.nih.gov/pubmed/26337677 http://dx.doi.org/10.1186/s12859-015-0698-6 |