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CoSREM: a graph mining algorithm for the discovery of combinatorial splicing regulatory elements

BACKGROUND: Alternative splicing (AS) is a post-transcriptional regulatory mechanism for gene expression regulation. Splicing decisions are affected by the combinatorial behavior of different splicing factors that bind to multiple binding sites in exons and introns. These binding sites are called sp...

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Detalles Bibliográficos
Autores principales: Badr, Eman, Heath, Lenwood S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559876/
https://www.ncbi.nlm.nih.gov/pubmed/26337677
http://dx.doi.org/10.1186/s12859-015-0698-6

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