Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo

BACKGROUND: Colorectal cancer (CRC) is a major health problem in China and around the world. It is one of the leading causes of cancer-related deaths. Research groups are thus searching for novel and more efficient anti-CRC agents. RESULTS: Here we demonstrated that ABC294640, a novel SphK2 inhibito...

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Detalles Bibliográficos
Autores principales: Xun, Cai, Chen, Min-Bin, Qi, Li, Tie-Ning, Zhang, Peng, Xue, Ning, Li, Zhi-Xiao, Chen, Li-Wei, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559903/
https://www.ncbi.nlm.nih.gov/pubmed/26337959
http://dx.doi.org/10.1186/s13046-015-0205-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559903/
https://www.ncbi.nlm.nih.gov/pubmed/26337959
http://dx.doi.org/10.1186/s13046-015-0205-y

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