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Genome-wide detection of intervals of genetic heterogeneity associated with complex traits

Motivation: Genetic heterogeneity, the fact that several sequence variants give rise to the same phenotype, is a phenomenon that is of the utmost interest in the analysis of complex phenotypes. Current approaches for finding regions in the genome that exhibit genetic heterogeneity suffer from at lea...

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Detalles Bibliográficos
Autores principales: Llinares-López, Felipe, Grimm, Dominik G., Bodenham, Dean A., Gieraths, Udo, Sugiyama, Mahito, Rowan, Beth, Borgwardt, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559912/
https://www.ncbi.nlm.nih.gov/pubmed/26072488
http://dx.doi.org/10.1093/bioinformatics/btv263