Cargando…
Hippocampal administration of chondroitinase ABC increases plaque-adjacent synaptic marker and diminishes amyloid burden in aged APPswe/PS1dE9 mice
INTRODUCTION: Substantial data has shown that the lectican group of chondroitin sulfate proteoglycans are involved in inhibition of axonal plasticity in response to injury in the central nervous system. Increasing evidence indicates that lecticans may also play a role in synaptic plasticity related...
Autores principales: | Howell, Matthew D., Bailey, Lauren A., Cozart, Michael A., Gannon, Brenda M., Gottschall, Paul E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559967/ https://www.ncbi.nlm.nih.gov/pubmed/26337292 http://dx.doi.org/10.1186/s40478-015-0233-z |
Ejemplares similares
-
Targeting chondroitinase ABC to axons enhances the ability of chondroitinase to promote neurite outgrowth and sprouting
por: Day, Priscilla, et al.
Publicado: (2020) -
Sustained Delivery of Chondroitinase ABC from Hydrogel System
por: Rossi, Filippo, et al.
Publicado: (2012) -
Diminished Perisomatic GABAergic Terminals on Cortical Neurons Adjacent to Amyloid Plaques
por: Garcia-Marin, Virginia, et al.
Publicado: (2009) -
Chondroitinase ABC improves recovery of long sciatic nerve defects☆
por: Yu, Hailong, et al.
Publicado: (2012) -
Substrate Specificity and Biochemical Characteristics
of an Engineered Mammalian Chondroitinase ABC
por: Warren, Philippa M., et al.
Publicado: (2021)