Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons

Previous studies have revealed a critical role for CREB-regulated transcriptional coactivator (CRTC1) in regulating neuronal gene expression during learning and memory. CRTC1 localizes to synapses but undergoes activity-dependent nuclear translocation to regulate the transcription of CREB target gen...

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Detalles Bibliográficos
Autores principales: Ch'ng, Toh Hean, DeSalvo, Martina, Lin, Peter, Vashisht, Ajay, Wohlschlegel, James A., Martin, Kelsey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560099/
https://www.ncbi.nlm.nih.gov/pubmed/26388727
http://dx.doi.org/10.3389/fnmol.2015.00048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560099/
https://www.ncbi.nlm.nih.gov/pubmed/26388727
http://dx.doi.org/10.3389/fnmol.2015.00048

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