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Repeat-swap homology modeling of secondary active transporters: updated protocol and prediction of elevator-type mechanisms

Secondary active transporters are critical for neurotransmitter clearance and recycling during synaptic transmission and uptake of nutrients. These proteins mediate the movement of solutes against their concentration gradients, by using the energy released in the movement of ions down pre-existing c...

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Detalles Bibliográficos
Autores principales: Vergara-Jaque, Ariela, Fenollar-Ferrer, Cristina, Kaufmann, Desirée, Forrest, Lucy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560100/
https://www.ncbi.nlm.nih.gov/pubmed/26388773
http://dx.doi.org/10.3389/fphar.2015.00183