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Repeat-swap homology modeling of secondary active transporters: updated protocol and prediction of elevator-type mechanisms
Secondary active transporters are critical for neurotransmitter clearance and recycling during synaptic transmission and uptake of nutrients. These proteins mediate the movement of solutes against their concentration gradients, by using the energy released in the movement of ions down pre-existing c...
Autores principales: | Vergara-Jaque, Ariela, Fenollar-Ferrer, Cristina, Kaufmann, Desirée, Forrest, Lucy R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560100/ https://www.ncbi.nlm.nih.gov/pubmed/26388773 http://dx.doi.org/10.3389/fphar.2015.00183 |
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