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Are there dynamical effects in enzyme catalysis? Some thoughts concerning the enzymatic chemical step

We offer some thoughts on the much debated issue of dynamical effects in enzyme catalysis, and more specifically on their potential role in the acceleration of the chemical step. Since the term ‘dynamics’ has been used with different meanings, we find it useful to first return to the Transition Stat...

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Detalles Bibliográficos
Autores principales: Tuñón, Iñaki, Laage, Damien, Hynes, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560206/
https://www.ncbi.nlm.nih.gov/pubmed/26087289
http://dx.doi.org/10.1016/j.abb.2015.06.004