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Porphyromonas gingivalis Type IX Secretion Substrates Are Cleaved and Modified by a Sortase-Like Mechanism

The type IX secretion system (T9SS) of Porphyromonas gingivalis secretes proteins possessing a conserved C-terminal domain (CTD) to the cell surface. The C-terminal signal is essential for these proteins to translocate across the outer membrane via the T9SS. On the surface the CTD of these proteins...

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Detalles Bibliográficos
Autores principales: Gorasia, Dhana G., Veith, Paul D., Chen, Dina, Seers, Christine A., Mitchell, Helen A., Chen, Yu-Yen, Glew, Michelle D., Dashper, Stuart G., Reynolds, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560394/
https://www.ncbi.nlm.nih.gov/pubmed/26340749
http://dx.doi.org/10.1371/journal.ppat.1005152