A Neoglycoconjugate Containing the Human Milk Sugar LNFPIII Drives Anti-Inflammatory Activation of Antigen Presenting Cells in a CD14 Dependent Pathway

The milk pentasaccharide LNFPIII has therapeutic action for metabolic and autoimmune diseases and prolongs transplant survival in mice when presented as a neoglycoconjugate. Within LNFPIII is the Lewis(x) trisaccharide, expressed by many helminth parasites. In humans, LNFPIII is found in human milk...

Descripción completa

Detalles Bibliográficos
Autores principales: Tundup, Smanla, Srivastava, Leena, Norberg, Thomas, Watford, Wendy, Harn, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560409/
https://www.ncbi.nlm.nih.gov/pubmed/26340260
http://dx.doi.org/10.1371/journal.pone.0137495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560409/
https://www.ncbi.nlm.nih.gov/pubmed/26340260
http://dx.doi.org/10.1371/journal.pone.0137495

Ejemplares similares