Ethyl Pyruvate Emerges as a Safe and Fast Acting Agent against Trypanosoma brucei by Targeting Pyruvate Kinase Activity

BACKGROUND: Human African Trypanosomiasis (HAT) also called sleeping sickness is an infectious disease in humans caused by an extracellular protozoan parasite. The disease, if left untreated, results in 100% mortality. Currently available drugs are full of severe drawbacks and fail to escape the fas...

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Detalles Bibliográficos
Autores principales: Worku, Netsanet, Stich, August, Daugschies, Arwid, Wenzel, Iris, Kurz, Randy, Thieme, Rene, Kurz, Susanne, Birkenmeier, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560413/
https://www.ncbi.nlm.nih.gov/pubmed/26340747
http://dx.doi.org/10.1371/journal.pone.0137353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560413/
https://www.ncbi.nlm.nih.gov/pubmed/26340747
http://dx.doi.org/10.1371/journal.pone.0137353

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