Cargando…
Exploring Strong Interactions in Proteins with Quantum Chemistry and Examples of Their Applications in Drug Design
OBJECTIVES: Three strong interactions between amino acid side chains (salt bridge, cation-π, and amide bridge) are studied that are stronger than (or comparable to) the common hydrogen bond interactions, and play important roles in protein-protein interactions. METHODS: Quantum chemical methods MP2...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560430/ https://www.ncbi.nlm.nih.gov/pubmed/26339784 http://dx.doi.org/10.1371/journal.pone.0137113 |