Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function

The nucleotide excision repair of certain bulky DNA lesions is abrogated in some specific non-canonical DNA base sequence contexts, while the removal of the same lesions by the nucleotide excision repair mechanism is efficient in duplexes in which all base pairs are complementary. Here we show that...

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Detalles Bibliográficos
Autores principales: Liu, Zhi, Ding, Shuang, Kropachev, Konstantin, Lei, Jia, Amin, Shantu, Broyde, Suse, Geacintov, Nicholas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560436/
https://www.ncbi.nlm.nih.gov/pubmed/26340000
http://dx.doi.org/10.1371/journal.pone.0137124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560436/
https://www.ncbi.nlm.nih.gov/pubmed/26340000
http://dx.doi.org/10.1371/journal.pone.0137124

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