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Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function
The nucleotide excision repair of certain bulky DNA lesions is abrogated in some specific non-canonical DNA base sequence contexts, while the removal of the same lesions by the nucleotide excision repair mechanism is efficient in duplexes in which all base pairs are complementary. Here we show that...
Autores principales: | Liu, Zhi, Ding, Shuang, Kropachev, Konstantin, Lei, Jia, Amin, Shantu, Broyde, Suse, Geacintov, Nicholas E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560436/ https://www.ncbi.nlm.nih.gov/pubmed/26340000 http://dx.doi.org/10.1371/journal.pone.0137124 |
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