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CXCR4 in breast cancer: oncogenic role and therapeutic targeting

Chemokines are 8–12 kDa peptides that function as chemoattractant cytokines and are involved in cell activation, differentiation, and trafficking. Chemokines bind to specific G-protein-coupled seven-span transmembrane receptors. Chemokines play a fundamental role in the regulation of a variety of ce...

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Detalles Bibliográficos
Autores principales: Xu, Chao, Zhao, Hong, Chen, Haitao, Yao, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560524/
https://www.ncbi.nlm.nih.gov/pubmed/26356032
http://dx.doi.org/10.2147/DDDT.S84932