Ultrasound-assisted non-viral gene transfer of AQP1 to the irradiated minipig parotid gland restores fluid secretion

RATIONALE: Xerostomia is a common side effect of ionizing radiation used to treat head and neck cancer. A groundbreaking Phase I human clinical trial utilizing Adenoviral gene transfer of Aquaporin-1 (AQP1) to a single salivary gland of individuals suffering from radiation-induced xerostomia has rec...

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Detalles Bibliográficos
Autores principales: Wang, Z, Zourelias, L, Wu, C, Edwards, PC, Trombetta, M, Passineau, MJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560616/
https://www.ncbi.nlm.nih.gov/pubmed/25871828
http://dx.doi.org/10.1038/gt.2015.36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560616/
https://www.ncbi.nlm.nih.gov/pubmed/25871828
http://dx.doi.org/10.1038/gt.2015.36

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