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Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome
Substrates are targeted for proteasomal degradation through the attachment of ubiquitin chains that need to be removed by proteasomal deubiquitinases prior to substrate processing. In budding yeast, the deubiquitinase Ubp6 trims ubiquitin chains and affects substrate processing by the proteasome, bu...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560640/ https://www.ncbi.nlm.nih.gov/pubmed/26301997 http://dx.doi.org/10.1038/nsmb.3075 |