Cargando…

Dipeptide species regulate p38MAPK–Smad3 signalling to maintain chronic myelogenous leukaemia stem cells

Understanding the specific survival of the rare chronic myelogenous leukaemia (CML) stem cell population could provide a target for therapeutics aimed at eradicating these cells. However, little is known about how survival signalling is regulated in CML stem cells. In this study, we survey global me...

Descripción completa

Detalles Bibliográficos
Autores principales: Naka, Kazuhito, Jomen, Yoshie, Ishihara, Kaori, Kim, Junil, Ishimoto, Takahiro, Bae, Eun-Jin, Mohney, Robert P., Stirdivant, Steven M., Oshima, Hiroko, Oshima, Masanobu, Kim, Dong-Wook, Nakauchi, Hiromitsu, Takihara, Yoshihiro, Kato, Yukio, Ooshima, Akira, Kim, Seong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560789/
https://www.ncbi.nlm.nih.gov/pubmed/26289811
http://dx.doi.org/10.1038/ncomms9039