Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation

Centrosome overduplication promotes mitotic abnormalities, invasion and tumorigenesis. Cells regulate the number of centrosomes by limiting centriole duplication to once per cell cycle. The orthogonal orientation between a mother and a daughter centriole, established at the time of centriole duplica...

Descripción completa

Detalles Bibliográficos
Autores principales: Shukla, Anil, Kong, Dong, Sharma, Meena, Magidson, Valentin, Loncarek, Jadranka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560806/
https://www.ncbi.nlm.nih.gov/pubmed/26293378
http://dx.doi.org/10.1038/ncomms9077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560806/
https://www.ncbi.nlm.nih.gov/pubmed/26293378
http://dx.doi.org/10.1038/ncomms9077

Ejemplares similares