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Dual-topology insertion of a dual-topology membrane protein
Some membrane transporters are dual-topology dimers in which the subunits have inverted transmembrane topology. How a cell manages to generate equal populations of two opposite topologies from the same polypeptide chain remains unclear. For the dual-topology transporter EmrE, the evidence to date re...
Autores principales: | Woodall, Nicholas B., Yin, Ying, Bowie, James U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560821/ https://www.ncbi.nlm.nih.gov/pubmed/26306475 http://dx.doi.org/10.1038/ncomms9099 |
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