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JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis

Planar spindle orientation in polarized epithelial cells depends on the precise localization of the dynein–dynactin motor protein complex at the lateral cortex. The contribution of cell adhesion molecules to the cortical localization of the dynein–dynactin complex is poorly understood. Here we find...

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Detalles Bibliográficos
Autores principales: Tuncay, Hüseyin, Brinkmann, Benjamin F., Steinbacher, Tim, Schürmann, Annika, Gerke, Volker, Iden, Sandra, Ebnet, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560831/
https://www.ncbi.nlm.nih.gov/pubmed/26306570
http://dx.doi.org/10.1038/ncomms9128