Cargando…
JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis
Planar spindle orientation in polarized epithelial cells depends on the precise localization of the dynein–dynactin motor protein complex at the lateral cortex. The contribution of cell adhesion molecules to the cortical localization of the dynein–dynactin complex is poorly understood. Here we find...
Autores principales: | Tuncay, Hüseyin, Brinkmann, Benjamin F., Steinbacher, Tim, Schürmann, Annika, Gerke, Volker, Iden, Sandra, Ebnet, Klaus |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560831/ https://www.ncbi.nlm.nih.gov/pubmed/26306570 http://dx.doi.org/10.1038/ncomms9128 |
Ejemplares similares
-
aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation
por: Iden, Sandra, et al.
Publicado: (2012) -
Cdc42 turns the spindle
por: Leslie, Mitch
Publicado: (2008) -
Junctional Adhesion Molecules (JAMs): The JAM-Integrin Connection
por: Kummer, Daniel, et al.
Publicado: (2018) -
Dynein light chain 1 and a spindle-associated adaptor promote dynein asymmetry and spindle orientation
por: Dunsch, Anja K., et al.
Publicado: (2012) -
Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis
por: Jaffe, Aron B., et al.
Publicado: (2008)