Sialic acid catabolism drives intestinal inflammation and microbial dysbiosis in mice

Rapid shifts in microbial composition frequently occur during intestinal inflammation, but the mechanisms underlying such changes remain elusive. Here we demonstrate that an increased caecal sialidase activity is critical in conferring a growth advantage for some bacteria including Escherichia coli...

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Detalles Bibliográficos
Autores principales: Huang, Yen-Lin, Chassard, Christophe, Hausmann, Martin, von Itzstein, Mark, Hennet, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560832/
https://www.ncbi.nlm.nih.gov/pubmed/26303108
http://dx.doi.org/10.1038/ncomms9141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560832/
https://www.ncbi.nlm.nih.gov/pubmed/26303108
http://dx.doi.org/10.1038/ncomms9141

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