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Alterations in serum microRNA in humans with alcohol use disorders impact cell proliferation and cell death pathways and predict structural and functional changes in brain

BACKGROUND: There is currently a lack of reliable, minimally invasive biomarkers that could predict the extent of alcoholism-induced CNS damage. Developing such biomarkers may prove useful in reducing the prevalence of alcohol use disorders (AUDs). Extracellular microRNAs (miRNAs) can be informative...

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Detalles Bibliográficos
Autores principales: Ignacio, Cherry, Hicks, Steven D., Burke, Patrick, Lewis, Lambert, Szombathyne-Meszaros, Zsuzsa, Middleton, Frank A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560885/
https://www.ncbi.nlm.nih.gov/pubmed/26341662
http://dx.doi.org/10.1186/s12868-015-0195-x