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Population Pharmacokinetics and Pharmacodynamics of GSK961081 (Batefenterol), a Muscarinic Antagonist and β(2)-Agonist, in Moderate-to-Severe COPD Patients: Substudy of a Randomized Trial

GSK961081 (batefenterol) is a novel bifunctional molecule composed of a muscarinic antagonist and a β(2)‐agonist. The aims of this substudy were (1) to characterize the population pharmacokinetics (PK) and pharmacodynamics (PD) of GSK961081 in patients with moderate-to-severe chronic obstructive pul...

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Detalles Bibliográficos
Autores principales: Ambery, Claire L., Wielders, Pascal, Ludwig-Sengpiel, Andrea, Chan, Robert, Riley, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561049/
https://www.ncbi.nlm.nih.gov/pubmed/26286203
http://dx.doi.org/10.1007/s40268-015-0104-x