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X Inactivation Lessons from Differentiating Mouse Embryonic Stem Cells

X chromosome inactivation (XCI) is the dosage compensation mechanism that evolved in female mammals to correct the genetic imbalance of X-linked genes between sexes. X chromosome inactivation occurs in early development when one of the two X chromosomes of females is nearly-completely silenced. Diff...

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Detalles Bibliográficos
Autores principales: Pintacuda, Greta, Cerase, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561061/
https://www.ncbi.nlm.nih.gov/pubmed/26198263
http://dx.doi.org/10.1007/s12015-015-9597-5