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The EML4-ALK oncogene: targeting an essential growth driver in human cancer

Targeting of essential growth drivers represents an ideal approach to cancer treatment. To identify such molecules in clinical specimens, we developed a highly sensitive functional screening system based on the preparation of retroviral cDNA expression libraries. By screening such a library of lung...

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Detalles Bibliográficos
Autor principal: MANO, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561238/
https://www.ncbi.nlm.nih.gov/pubmed/25971657
http://dx.doi.org/10.2183/pjab.91.193