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Comparison of Monkeypox Virus Clade Kinetics and Pathology within the Prairie Dog Animal Model Using a Serial Sacrifice Study Design

Monkeypox virus (MPXV) infection of the prairie dog is valuable to studying systemic orthopoxvirus disease. To further characterize differences in MPXV clade pathogenesis, groups of prairie dogs were intranasally infected (8 × 10(3) p.f.u.) with Congo Basin (CB) or West African (WA) MPXV, and 28 tis...

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Detalles Bibliográficos
Autores principales: Hutson, Christina L., Carroll, Darin S., Gallardo-Romero, Nadia, Drew, Clifton, Zaki, Sherif R., Nagy, Tamas, Hughes, Christine, Olson, Victoria A., Sanders, Jeanine, Patel, Nishi, Smith, Scott K., Keckler, M. Shannon, Karem, Kevin, Damon, Inger K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561332/
https://www.ncbi.nlm.nih.gov/pubmed/26380309
http://dx.doi.org/10.1155/2015/965710