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An introductory review of parallel independent component analysis (p-ICA) and a guide to applying p-ICA to genetic data and imaging phenotypes to identify disease-associated biological pathways and systems in common complex disorders

Complex inherited phenotypes, including those for many common medical and psychiatric diseases, are most likely underpinned by multiple genes contributing to interlocking molecular biological processes, along with environmental factors (Owen et al., 2010). Despite this, genotyping strategies for com...

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Detalles Bibliográficos
Autores principales: Pearlson, Godfrey D., Liu, Jingyu, Calhoun, Vince D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561364/
https://www.ncbi.nlm.nih.gov/pubmed/26442095
http://dx.doi.org/10.3389/fgene.2015.00276