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LAPTM4B is associated with poor prognosis in NSCLC and promotes the NRF2-mediated stress response pathway in lung cancer cells

We recently demonstrated that lysosomal protein transmembrane 4 beta (LAPTM4B) is elevated in non-small cell lung cancers (NSCLCs) and in the surrounding premalignant airway field of cancerization. In the present study, we sought to begin to understand the relevance of LAPTM4B expression and signali...

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Detalles Bibliográficos
Autores principales: Maki, Yuho, Fujimoto, Junya, Lang, Wenhua, Xu, Li, Behrens, Carmen, Wistuba, Ignacio I., Kadara, Humam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561374/
https://www.ncbi.nlm.nih.gov/pubmed/26343532
http://dx.doi.org/10.1038/srep13846