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LAPTM4B is associated with poor prognosis in NSCLC and promotes the NRF2-mediated stress response pathway in lung cancer cells
We recently demonstrated that lysosomal protein transmembrane 4 beta (LAPTM4B) is elevated in non-small cell lung cancers (NSCLCs) and in the surrounding premalignant airway field of cancerization. In the present study, we sought to begin to understand the relevance of LAPTM4B expression and signali...
Autores principales: | Maki, Yuho, Fujimoto, Junya, Lang, Wenhua, Xu, Li, Behrens, Carmen, Wistuba, Ignacio I., Kadara, Humam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561374/ https://www.ncbi.nlm.nih.gov/pubmed/26343532 http://dx.doi.org/10.1038/srep13846 |
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