Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes

G-quadruplexes (G4) are extremely stable secondary structures forming stacks of guanine tetrads. DNA G4 structures have been extensively studied, however, less is known about G4 motifs in mRNAs, especially in their coding sequences. Herein, we show that Aven stimulates the mRNA translation of the mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Thandapani, Palaniraja, Song, Jingwen, Gandin, Valentina, Cai, Yutian, Rouleau, Samuel G, Garant, Jean-Michel, Boisvert, Francois-Michel, Yu, Zhenbao, Perreault, Jean-Pierre, Topisirovic, Ivan, Richard, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561382/
https://www.ncbi.nlm.nih.gov/pubmed/26267306
http://dx.doi.org/10.7554/eLife.06234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561382/
https://www.ncbi.nlm.nih.gov/pubmed/26267306
http://dx.doi.org/10.7554/eLife.06234

Ejemplares similares