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Surface-Induced Polymorphism as a Tool for Enhanced Dissolution: The Example of Phenytoin
[Image: see text] Polymorphism and morphology can represent key factors tremendously limiting the bioavailability of active pharmaceutical ingredients (API), in particular, due to solubility issues. Within this work, the generation of a yet unknown surface-induced polymorph (SIP) of the model drug,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561386/ https://www.ncbi.nlm.nih.gov/pubmed/26366128 http://dx.doi.org/10.1021/acs.cgd.5b01002 |