Free fatty acid receptors: structural models and elucidation of ligand binding interactions

BACKGROUND: The free fatty acid receptors (FFAs), including FFA1 (orphan name: GPR40), FFA2 (GPR43) and FFA3 (GPR41) are G protein-coupled receptors (GPCRs) involved in energy and metabolic homeostasis. Understanding the structural basis of ligand binding at FFAs is an essential step toward designin...

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Detalles Bibliográficos
Autores principales: Tikhonova, Irina G., Poerio, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561419/
https://www.ncbi.nlm.nih.gov/pubmed/26346819
http://dx.doi.org/10.1186/s12900-015-0044-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561419/
https://www.ncbi.nlm.nih.gov/pubmed/26346819
http://dx.doi.org/10.1186/s12900-015-0044-2

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