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Amplification of Cellular Oncogenes in Solid Tumors

The term gene amplification refers to an increase in copy number of a gene. Upregulation of gene expression through amplification is a general mechanism to increase gene dosage. Oncogene amplifications have been shown in solid human cancers and they are often associated with progression of cancer. D...

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Detalles Bibliográficos
Autores principales: Bagci, Ozkan, Kurtgöz, Serkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561439/
https://www.ncbi.nlm.nih.gov/pubmed/26417556
http://dx.doi.org/10.4103/1947-2714.163641