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Genome-wide annotation of microRNA primary transcript structures reveals novel regulatory mechanisms

Precise regulation of microRNA (miRNA) expression is critical for diverse physiologic and pathophysiologic processes. Nevertheless, elucidation of the mechanisms through which miRNA expression is regulated has been greatly hindered by the incomplete annotation of primary miRNA (pri-miRNA) transcript...

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Detalles Bibliográficos
Autores principales: Chang, Tsung-Cheng, Pertea, Mihaela, Lee, Sungyul, Salzberg, Steven L., Mendell, Joshua T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561498/
https://www.ncbi.nlm.nih.gov/pubmed/26290535
http://dx.doi.org/10.1101/gr.193607.115