CRISPR adaptation biases explain preference for acquisition of foreign DNA

In the process of CRISPR adaptation, short pieces of DNA (“spacers”) are acquired from foreign elements and integrated into the CRISPR array. It so far remained a mystery how spacers are preferentially acquired from the foreign DNA while the self chromosome is avoided. Here we show that spacer acqui...

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Detalles Bibliográficos
Autores principales: Levy, Asaf, Goren, Moran G., Yosef, Ido, Auster, Oren, Manor, Miriam, Amitai, Gil, Edgar, Rotem, Qimron, Udi, Sorek, Rotem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561520/
https://www.ncbi.nlm.nih.gov/pubmed/25874675
http://dx.doi.org/10.1038/nature14302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561520/
https://www.ncbi.nlm.nih.gov/pubmed/25874675
http://dx.doi.org/10.1038/nature14302

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