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Fine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at work
Ubiquitination is a reversible protein modification broadly implicated in cellular functions. Signaling processes mediated by ubiquitin (ub) are crucial for the cellular response to DNA double-strand breaks (DSBs), one of the most dangerous types of DNA lesions. In particular, the DSB response criti...
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Μορφή: | Online Άρθρο Κείμενο |
Γλώσσα: | English |
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Frontiers Media S.A.
2015
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Διαθέσιμο Online: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561801/ https://www.ncbi.nlm.nih.gov/pubmed/26442100 http://dx.doi.org/10.3389/fgene.2015.00282 |