Modeling the interplay between the HIF-1 and p53 pathways in hypoxia

Both the hypoxia-inducible factor-1 (HIF-1) and tumor suppressor p53 are involved in the cellular response to hypoxia. How the two transcription factors interact to determine cell fates is less well understood. Here, we developed a network model to characterize crosstalk between the HIF-1 and p53 pa...

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Detalles Bibliográficos
Autores principales: Zhou, Chun-Hong, Zhang, Xiao-Peng, Liu, Feng, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561886/
https://www.ncbi.nlm.nih.gov/pubmed/26346319
http://dx.doi.org/10.1038/srep13834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561886/
https://www.ncbi.nlm.nih.gov/pubmed/26346319
http://dx.doi.org/10.1038/srep13834

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