Geranylgeranylacetone selectively binds to the HSP70 of Helicobacter pylori and alters its coccoid morphology

Geranylgeranylacetone (GGA) is used to treat patients suffering from peptic ulcers and gastritis. We examined the effect of GGA on Helicobacter pylori, which is a causative factor of gastrointestinal diseases. Previously, we have reported that GGA binds specifically to the molecular chaperone HSP70....

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Detalles Bibliográficos
Autores principales: Grave, Ewa, Yokota, Shin-ichi, Yamamoto, Soh, Tamura, Arisa, Ohtaki-Mizoguchi, Takako, Yokota, Kenji, Oguma, Keiji, Fujiwara, Kazuhiko, Ogawa, Nobuaki, Okamoto, Tomoya, Otaka, Michiro, Itoh, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561889/
https://www.ncbi.nlm.nih.gov/pubmed/26345206
http://dx.doi.org/10.1038/srep13738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561889/
https://www.ncbi.nlm.nih.gov/pubmed/26345206
http://dx.doi.org/10.1038/srep13738

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