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Natural Killer Cells-Produced IFN-γ Improves Bone Marrow-Derived Hepatocytes Regeneration in Murine Liver Failure Model

Bone-marrow transplantation (BMT) can repopulate the liver through BM-derived hepatocyte (BMDH) generation, although the underlying mechanism remains unclear. Using fumarylacetoacetate hydrolase–deficient (Fah(−/−)) mice as a liver-failure model, we confirmed that BMDHs were generated by fusion of B...

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Detalles Bibliográficos
Autores principales: Li, Lu, Zeng, Zhutian, Qi, Ziping, Wang, Xin, Gao, Xiang, Wei, Haiming, Sun, Rui, Tian, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561890/
https://www.ncbi.nlm.nih.gov/pubmed/26345133
http://dx.doi.org/10.1038/srep13687