Physical Intimacy of Breast Cancer Cells with Mesenchymal Stem Cells Elicits Trastuzumab Resistance through Src Activation

The development of resistance to trastuzumab is a major obstacle for lasting effective treatment of patients with ErbB2-overexpressing tumors. Here, we demonstrate that the physical contact of breast cancer cells with mesenchymal stem cells (MSCs) is a potential modulator of trastuzumab response by...

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Detalles Bibliográficos
Autores principales: Daverey, Amita, Drain, Allison P., Kidambi, Srivatsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561910/
https://www.ncbi.nlm.nih.gov/pubmed/26345302
http://dx.doi.org/10.1038/srep13744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561910/
https://www.ncbi.nlm.nih.gov/pubmed/26345302
http://dx.doi.org/10.1038/srep13744

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