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HIV-1 Tat and cocaine mediated synaptopathy in cortical and midbrain neurons is prevented by the isoflavone Equol

Illicit drugs, such as cocaine, are known to increase the likelihood and severity of HIV-1 associated neurocognitive disorders (HAND). In the current studies synaptic integrity was assessed following exposure to low concentrations of the HIV-1 viral protein Tat 1-86B, with or without cocaine, by qua...

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Detalles Bibliográficos
Autores principales: Bertrand, Sarah J., Hu, Calvin, Aksenova, Marina V., Mactutus, Charles F., Booze, Rosemarie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561964/
https://www.ncbi.nlm.nih.gov/pubmed/26441850
http://dx.doi.org/10.3389/fmicb.2015.00894