Landmark studies on the glucagon subfamily of GPCRs: from small molecule modulators to a crystal structure

The glucagon subfamily of class B G protein-coupled receptors (GPCRs) has been proposed to be a crucial drug target for the tretmaent of type 2 diabetes. The challenges associated with determining the crystal structures of class B GPCRs relate to their large amino termini and the lack of available s...

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Detalles Bibliográficos
Autores principales: Yang, De-hua, Zhou, Cai-hong, Liu, Qing, Wang, Ming-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561977/
https://www.ncbi.nlm.nih.gov/pubmed/26279155
http://dx.doi.org/10.1038/aps.2015.78

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561977/
https://www.ncbi.nlm.nih.gov/pubmed/26279155
http://dx.doi.org/10.1038/aps.2015.78

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